CAS: 1139-30-6
FEMA No: 4085
Caryophyllene oxide is an oxygenated terpenoid, usually a metabolic by product of caryophyllene. It’s use as an antifungal is highly effective with certain species. In addition, caryophyllene oxide has also been indicated as an anticoagulant with platelets
ATTRIBUTES
Sources
Lemon Balm, Black Caraway, Cloves, Hops, Basil, Oregano, Black Pepper, West African Pepper, Lavender, Rosemary, Cinnamomum, Malabathrum, Cananga Odorata, Copaiba Oil
Aroma
Dry, Fresh, Spicy, Sweet, Woody
Flavor Profile
Herb, Must, Spice, Wood
Benefit
Research
Antifungal
Commonly used as preservative in food, drugs, and cosmetics. Its antifungal activity has been compared to ciclopiroxolamine and sulconazole, mainly used in onychomycosis treatment and dermatophytes.
Anticoagulant
Caryophyllene oxide isolated from the rhizome of Formosan Gynura japonica was shown to exhibit significant anti-platelet aggregation activity in vitro.
Anti-Platelet Aggregation and Chemical Constituents from the Rhizome of Gynura japonica
synergy
Synergistic effects with…
Cannabinoids
Antifungal - CBC, CBG
Anticoagulant - THC
Insecticidal - THCA, CBGA
SCIENCE
- Formula: C15H24O
- Molecular Mass: 220.35 g/mol
- Melting Point: 60.00 C - 62.00 C
- Boiling Point: 279.68 C
- Flash Point: > 212.00 F
Synonyms
Caryophyllene Oxide is also know by these other names
- 1139-30-6 [RN]
- β-Caryophyllene oxide
- b-Caryophyllene oxide
- (−)-Epoxycaryophyllene
- b-Caryophyllene epoxide
- (−)-Caryophyllene oxide
- 4b,5a-Epoxycaryophyllene
- (-)-b-Caryophyllene oxide
- Caryophyllene 4b,5a-oxide
- trans-caryophyllene oxide
- (-)-β-Caryophyllene epoxide
- (-)-b-Caryophyllene epoxide
- 6,7-Epoxy-3(15)-caryophyllene
- (-)-Epoxydihydrocaryophyllene
- (1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane
- 5-Oxatricyclo(8.2.0.0(4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
- (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane [ACD/IUPAC Name]
- 5-Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- [ACD/Index Name]
SAFETY
LD50: Rat > 5,000 mg/kg
Storage: Store in cool, dry place in tightly sealed containers, protected from heat and light
sponsored
DISCUSSION
Read through our forum on Caryophyllene Oxide below, or start your own topic.